0:00Predictive genomics is the science of using knowledge about an individual's genomic data to predict his or her risk of developing specific diseases or experiencing adverse drug reactions to medications.
0:15It has the potential to revolutionize healthcare by providing personalized preventive healthcare plans that shift from treating sick people to helping reduce their risk of getting sick, improving health outcomes, and help to reduce overall healthcare costs.
0:33Microarray technology is a practical, highly accurate, and cost-effective solution. Genotyping using microarray arrays involve hybridizing a DNA sample onto thousands of oligonucleotide probes attached to a solid support, yielding a signal that reveals genetic variation in a given sample. Population genotyping micro arrays enable researchers to investigate thousands of variants for any specific population accurately, quickly, and cost-effectively.
1:48There is a reason many of the world's largest population genomics and preemptive pharmacogenomics research initiatives have been established on the Applied Bio systems Aum genotyping solution.
2:01Aum micro arrays can be tailored for specific disease risk or population demographics, and they are practical, cost-effective, scalable, and highly accurate.
2:14With Aum micro arrays, researchers can directly genotype hundreds of thousands of variants associated with genetic diseases, traits, and biological functions with very high accuracy. Develop imputation aware designs that enable researchers to expand their view to millions of markers.
2:46Customize and optimize their own array designs easily and cost effectively. Add, remove, or replace markers from your own database or the Aum genomic database at any time over the course of a longitudinal study.
3:35The total Aum microarray solution provides comprehensive analysis from sample through reporting. The Applied Bio Systems gene Titan multichannel instrument accelerates microarray processing with integrated hybridization, washing, and imaging. The Aum micro arrays are available with content for a broad range of predictive genomics research applications and can also be customized to create your own genotyping array designs.
4:08The Applied Bio Systems Aum analysis suite software integrates sample QC, variant QC, genotyping, and other types of variant summary reports, such as translation reports and carrier reports into a single user interface.
5:07Advancements in microarray technologies offer opportunities to gain new insights into genetic diseases, traits, and biological functions quickly and cost-effectively for predictive genomic research studies of any scope or scale. More targeted research in diagnosis, prognosis, and treatment strategies may also enable better health outcomes in the future and help reduce the overall costs of healthcare.
